Isoquinoline, 5-chloro-1,2,3,4-tetrahydro- - Names and Identifiers
Name | 5-Chloro-1,2,3,4-tetrahydroisoquinoline
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Synonyms | C90102 5-Chloro-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 5-chloro-1,2,3,4-tetrahydro- isoquinoline, 5-chloro-1,2,3,4-tetrahydro-
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CAS | 73075-43-1
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InChI | InChI=1/C9H10ClN/c10-9-3-1-2-7-6-11-5-4-8(7)9/h1-3,11H,4-6H2 |
Isoquinoline, 5-chloro-1,2,3,4-tetrahydro- - Physico-chemical Properties
Molecular Formula | C9H10ClN
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Molar Mass | 167.64 |
Density | 1.162 |
Boling Point | 276 ºC |
Flash Point | 121 ºC |
Vapor Presure | 0.005mmHg at 25°C |
pKa | 8.94±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.56 |
Isoquinoline, 5-chloro-1,2,3,4-tetrahydro- - Introduction
5-Chloro-1,2,3,4-tetrahydroisoquinoline is an organic compound with the chemical formula C9H10ClN. The following is information about its nature, use, formulation and safety:
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in a variety of organic solvents, such as alcohols, ethers and chlorinated hydrocarbons.
-Density: about 1.12g/cm³
-Melting point: about -35°C
-Boiling point: about 220°C
-specific rotation: about 18 °
Use:
5-Chloro-1,2,3,4-tetrahydroisoquinoline is usually used as an intermediate in organic synthesis and can be used to synthesize a variety of drugs and other organic compounds. It has a heterocyclic structure and is commonly used in the synthesis of drugs containing isoquinoline skeleton, such as anti-nerve stimulation drugs, cholesterol-lowering drugs, etc.
Preparation Method:
5-Chloro-1,2,3,4-tetrahydroisoquinoline can be prepared by a variety of methods, including the reaction of hydrochloric acid and isoquinoline, the reaction of chlorinated hydrocarbons and isoquinoline, etc. The specific preparation method can be selected according to specific requirements and conditions.
Safety Information:
5-Chloro-1,2,3,4-tetrahydroisoquinoline is generally less toxic under normal handling. However, as an organic compound, it can pose a health and environmental hazard. During use, safety procedures should be followed and appropriate protective measures should be taken, such as wearing gloves, masks and goggles. In case of accidental contact or ingestion, seek medical attention immediately. Generally speaking, when using and storing chemicals, the relevant safety procedures and regulations should be strictly observed.
Last Update:2024-04-09 20:45:29